Molecular Epidemiology of Different Hepatitis C Genotypes in Serum and Peripheral Blood Mononuclear Cells in Jahrom City of Iran
نویسندگان
چکیده
منابع مشابه
Molecular Epidemiology of Different Hepatitis C Genotypes in Serum and Peripheral Blood Mononuclear Cells in Jahrom City of Iran
BACKGROUND The Hepatitis C Virus (HCV) is considered essentially hepatotropic, yet the virus compartments have also been found in important extra hepatic sites. Detection of HCV RNA in extra hepatic reservoirs such as peripheral blood mononuclear cells (PBMCs) is important for determining disease progression and treatment effectiveness. OBJECTIVES The present study aimed to determine differen...
متن کاملmolecular epidemiology of different hepatitis c genotypes in serum and peripheral blood mononuclear cells in jahrom city of iran
conclusions it is suggested that determination of the target genotype by plasma subtyping for choosing the proper antiviral therapy is essential but may result in therapy failure. hcv genotyping in pbmc samples, along with plasma specimens, might be more beneficial. therefore determining the hcv genotype in pbmcs, before beginning the therapy is useful due to the possibility of occult infection...
متن کاملComparison of Hepatitis C Genotypes in Plasma and Peripheral Blood Mononuclear Cells (PMBCs) in Hepatitis C-Infected Patients
Abstract Background and Aims: The Hepatitis C Virus (HCV) is essentially hepatotropic but virus compartment has also been found in other important extra hepatic sites. Detection of HCV RNA in extra hepatic reservoirs such as peripheral blood mononuclear cells (PBMCs) is important for determining of disease progression and effective treatment. The present study aimed to determine of differe...
متن کاملcomparison of hepatitis c genotypes in plasma and peripheral blood mononuclear cells (pmbcs) in hepatitis c-infected patients
aim and objectives: the hepatitis c virus (hcv) is essentially hepatotropic but virus compartment have also been found in other important extra hepatic sites. detection of hcv rna in extra hepatic reservoirs such as peripheral blood mononuclear cells (pbmcs) is important for determining of disease progression and effective treatment. the present study aimed to determining of different hcv genot...
متن کاملMolecular Epidemiology of Torque Teno Virus (TTV) Isolated from in Healthy and Subjects with Chronic Hepatitis B and C in Jahrom City of Iran
Background and Aims: Torque teno virus (TTV) is a DNA virus that isolated from the serum of a Japanese patient without A-G transfusion-transmitted hepatitis and other etiology. TTV is detectable in plasma and peripheral blood mononuclear cells, different body fluids and secretions such as stools, saliva, semen, vaginal fluid. The genome exhibits high diversity that has enabled the determination...
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ژورنال
عنوان ژورنال: Hepatitis Monthly
سال: 2014
ISSN: 1735-143X,1735-3408
DOI: 10.5812/hepatmon.16391